A 46-Year-Old Woman With Dyspnea From an Inhalational Exposure, Triggering...
Background:Thyroid storm is a rare, life-threatening condition which arises in patients with thyrotoxicosis, with an annual incidence of 2 patients per 1,000,000 and a mortality rate of 11%. Case:We...
View ArticleManagement of Atrial Fibrillation
Atrial fibrillation remains the most prevalent cardiac arrhythmia, and its incidence is increasing as the population ages. Common conditions associated with an increased incidence include advanced...
View ArticleThe Impact of Computed Tomography of the Chest on the Management of Patients...
Purpose:To understand whether chest computed tomographies (CTs) have utility in a medical intensive care unit (MICU) population as previously noted in nonmedical critically ill patients. Patients and...
View ArticleBrain Tissue Oxygen Monitoring in Neurocritical Care
Brain injury results from ischemia, tissue hypoxia, and a cascade of secondary events. The cornerstone of neurocritical care management is optimization and maintenance of cerebral blood flow (CBF) and...
View ArticleSurgical Management of Severe Colitis in the Intensive Care Unit
Severe colitis, an umbrella encompassing several entities, is one of the most common acute gastrointestinal disorders resulting in critical illness. Clostridium difficile infection is responsible for...
View ArticleA Review of and Recommendations for the Management of Patients With...
Dabigatran is an oral direct thrombin inhibitor that is approved for the prevention of stroke and systemic embolism in nonvalvular atrial fibrillation. Dabigatran has several advantages over warfarin...
View ArticleSafety of Propofol as an Induction Agent for Urgent Endotracheal Intubation...
Purpose:Propofol is known to provide excellent intubation conditions without the use of neuromuscular blocking agents. However, propofol has adverse effects that may limit its use in the critically ill...
View ArticleCardiovascular Effects of Continuous Dexmedetomidine Infusion Without a...
Background:Use of dexmedetomidine in pediatric critical care is common, despite lack of prospective studies on its hemodynamic effects. Objective:To describe cardiovascular effects in critically ill...
View ArticleEvidence-Based Management of Common Gallstone-Related Emergencies
Gallstone-related disease is among the most common clinical problems encountered worldwide. The manifestations of cholelithiasis vary greatly, ranging from mild biliary colic to life-threatening...
View ArticleSleep in the Intensive Care Unit: A Review
Patients in the intensive care unit (ICU) are susceptible to sleep deprivation. Disrupted sleep is associated with increased morbidity and mortality in the critically ill patients. The etiology of...
View ArticleA National Survey of Critical Care Physicians Knowledge, Attitudes, and...
Objective:Antimicrobial stewardship is a process designed to optimize antimicrobial therapy by ensuring patients get the right antimicrobials at the right dose and at the right time. Antimicrobial...
View ArticleCardiocerebral Resuscitation: An Approach to Improving Survival of Patients...
Out-of-hospital cardiac arrest (OHCA) is a major public health problem. In the United States, OHCA accounts for more premature deaths than any other cause. For over a half-century, the national...
View ArticleHypothalamic-Pituitary Function in Brain Death: A Review
The Uniform Determination of Death Act (UDDA) states that an individual is dead when "all functions of the entire brain" have ceased irreversibly. However, it has been questioned whether some...
View ArticleThe Modified Apnea Test During Brain Death Determination: An Alternative in...
Introduction:Conventional apnea testing in patients with severe hypoxemia or hemodynamic instability with removal from the ventilator support is unsafe. We describe an alternative approach to apnea...
View ArticleChest Radiological Findings of Patients With Severe H1N1 Pneumonia Requiring...
Introduction:A new strain of human influenza A (H1N1) virus originated from Mexico in 2009 and spread to more than 190 countries and territories. The World Health Organization (WHO) declared it a level...
View ArticleLong-Term Mortality After Pneumonia in Cardiac Surgery Patients: A...
Background:The role that intensive care unit (ICU)-acquired pneumonia plays in the long-term outcomes of cardiac surgery patients is not well known. This study examined the association of pneumonia...
View ArticleManagement of Complications of End-Stage Liver Disease in the Intensive Care...
The management of critically ill patients with end-stage liver disease can be challenging due to the vulnerability of this population and the wide-ranging complications of the disease. This review...
View ArticleSyncope
Syncope is common representing approximately 3% of ED visits and up to 6% of hospital admissions, with a cost close to 2 billion dollars per year. Diagnostic testing is often poorly sensitive and...
View ArticleDaytime Versus Nighttime Extubations: A Comparison of Reintubation, Length of...
Purpose:Despite studies regarding outcomes of day versus night medical care, consequences of nighttime extubations are unknown. It may be favorable to extubate patients off-hours, as soon as weaning...
View ArticleBiomarkers in Hepatic Disease: A Review Focused on Critically Ill Patients
The ability to make a diagnosis early and appropriately is paramount for the survival of the critically ill ICU patient. Along with the myriad physical examination and imaging modalities available,...
View ArticleA Review of Multifaceted Care Approaches for the Prevention and Mitigation of...
Objective:The objective of this review is to examine the effectiveness, implementation, and costs of multifaceted care approaches, including care bundles, for the prevention and mitigation of delirium...
View ArticleThe Use of Modafinil in the Intensive Care Unit
As patients recover from their critical illness, the focus of intensive care unit (ICU) care becomes rehabilitation. Fatigue, excessive daytime somnolence (EDS), and depression can delay their...
View ArticleTwo Methods of Hemodynamic and Volume Status Assessment in Critically Ill...
Introduction:The invasive nature and potential complications associated with pulmonary artery (PA) catheters (PACs) have prompted the pursuit of less invasive monitoring options. Before implementing...
View ArticleLow-Dose Ketamine in Chronic Critical Illness
We report a case series on the observed effects of low-dose ketamine infusions in 4 critically ill patients with varying complications related to prolonged critical illness. Doses of ketamine infusion...
View ArticleA Model for Identifying Patients Who May Not Need Neurologic Intensive Care...
Purpose:Limited resources, neurointensivists, and neurologic intensive care unit (neuro-ICU) beds warrant investigating models for predicting who will benefit from admission to neuro-ICU. This study...
View ArticleThe Effect of an Electronic Checklist on Critical Care Provider Workload,...
Purpose:The strategy used to improve effective checklist use in intensive care unit (ICU) setting is essential for checklist success. This study aimed to test the hypothesis that an electronic...
View ArticleThe Association Between Admission Magnesium Concentrations and Lactic...
Introduction:Although magnesium plays an important role in aerobic metabolism and magnesium deficiency is a common phenomenon in critical illness, the association between magnesium deficiency and...
View ArticleInfective Endocarditis
Infective endocarditis (IE) is a noncontagious infection of the endocardium and heart valves. The epidemiology of IE has shifted recently with an increase in health care-associated IE. Infective...
View ArticleDamage Control Resuscitation
Resuscitation of the hemorrhaging patient has undergone significant changes in the last decade resulting in the concept of damage control resuscitation (DCR). Hemostatic resuscitation aims to address...
View ArticleEvaluation of Early Dexmedetomidine Addition to the Standard of Care for...
Purpose:This study evaluated the impact of dexmedetomidine (DEX) administration on benzodiazepine (BZD) requirements in intensive care unit (ICU) patients experiencing alcohol withdrawal syndrome...
View ArticleAntibiotic Dosing in Patients With Acute Kidney Injury: "Enough But Not Too...
Increasing evidence suggests that antibiotic dosing in critically ill patients with acute kidney injury (AKI) often does not achieve pharmacodynamic goals, and the continued high mortality rate due to...
View ArticleA Technique for Bronchoscopic Intubation During High-Flow Nasal Cannula...
Despite preoxygenation, critical hypoxemia can occur during intubation. We describe a technique of high-flow nasal cannula oxygen support during bronchoscopic intubation
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